Takafumi MIKI, PhD (Professor)

Yosuke OKAMOTO, MD, PhD (Lecturer)

Yuji OKAMOTO, PhD (Assistant Professor)

Daiki KOBAYASHI (Technician)

1. Synaptic physiology
2. Synapse development
3. Synapse regeneration
4. Bioartificial synapses
5. Cardiac arrhythmia

(†equal contribution; *correspondence)

1. Miki T†*, Okamoto Y†, Ueno-Umegai M, Toyofuku R, Hattori S, Sakaba T. Single-vesicle imaging reveals actin-dependent spatial restriction of vesicles at the active zone, essential for sustained transmission. Proc Natl Acad Sci USA 121: e2402152121, 2024.
2. Okamoto Y*, Aung NY, Tanaka M, Takeda Y, Takagi D, Igarashi W, Ishii K, Yamakawa M, Ono K*. Preferential expression of Ca2+-stimulable adenylyl cyclase III in the supraventricular area, including arrhythmogenic pulmonary vein of the rat heart. Biomolecules. 12:724, 2022.
3. Tran V†*, Miki T†*, Marty A. Three small vesicular pools in sequence govern synaptic response dynamics during action potential trains. Proc Natl Acad Sci USA 119: e2114469119, 2022.
4. Tanaka M, Sakaba T, Miki T*. Quantal analysis estimates docking site occupancy determining short-term depression at hippocampal glutamatergic synapses. J Physiol 599: 5301-5327, 2021.
5. Vandael D†*, Okamoto Y†, Jonas P*. Transsynaptic modulation of presynaptic short-term plasticity in hippocampal mossy fiber synapses. Nat Commun 12:2912. 2021.
6. Miki T*, Midorikawa M, Sakaba T*. Direct imaging of rapid tethering of synaptic vesicles accompanying exocytosis at a fast central synapse. Proc Natl Acad Sci USA 117: 14493-14502, 2020.

Takafumi Miki, PhD (Professor)
+81 (0)18-884-6069 / [email protected]